Silencing DACH1 promotes esophageal cancer growth by inhibiting TGF-β signaling.

Human Dachshund homologue 1 (DACH1) is a major component of the Retinal Determination Gene Network. Loss of DACH1 expression was found in breast, prostate, lung, endometrial, colorectal and hepatocellular carcinoma. To explore the expression, regulation and function of DACH1 in human esophageal canc...

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Bibliographic Details
Main Authors: Liang Wu, James G Herman, Malcolm V Brock, Kongming Wu, Gaoping Mao, Wenji Yan, Yan Nie, Hao Liang, Qimin Zhan, Wen Li, Mingzhou Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24743895/pdf/?tool=EBI