The ocular conjunctiva as a mucosal immunization route: a profile of the immune response to the model antigen tetanus toxoid.

BACKGROUND: In a quest for a needle-free vaccine administration strategy, we evaluated the ocular conjunctiva as an alternative mucosal immunization route by profiling and comparing the local and systemic immune responses to the subcutaneous or conjunctival administration of tetanus toxoid (TTd), a...

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Bibliographic Details
Main Authors: Talin Barisani-Asenbauer, Aleksandra Inic-Kanada, Sandra Belij, Emilija Marinkovic, Ivana Stojicevic, Jacqueline Montanaro, Elisabeth Stein, Nora Bintner, Marijana Stojanovic
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3637207?pdf=render