Interleukin-17-Producing CD4+ T Cells Promote Inflammatory Response and Foster Disease Progression in Hyperlipidemic Patients and Atherosclerotic Mice

Interleukin-17-Producing CD4+ T Cells Promote Inflammatory Response and Foster Disease Progression in Hyperlipidemic Patients and Atherosclerotic Mice

Atherosclerosis is a chronic inflammatory disease. Interleukin-17-producing CD4+ T cells (Th17 cells) play important roles in the progression of atherosclerosis. However, most of the studies were focused on the advanced stage of atherosclerosis. In the current study, we investigated the roles of Th1...

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Bibliographic Details
Main Authors: Yin Wang, Wenming Li, Tingrui Zhao, Yao Zou, Tao Deng, Zhangyou Yang, Zhiyi Yuan, Limei Ma, Ruihong Yu, Tingting Wang, Chao Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
atherosclerosis
inflammation
interleukin-17-producing CD4+ T cells
macrophages
neutrophils
hyperlipidemia
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.667768/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2021.667768/full

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