Optimal plasticity for memory maintenance during ongoing synaptic change

Synaptic connections in many brain circuits fluctuate, exhibiting substantial turnover and remodelling over hours to days. Surprisingly, experiments show that most of this flux in connectivity persists in the absence of learning or known plasticity signals. How can neural circuits retain learned inf...

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Bibliographic Details
Main Authors: Dhruva V Raman, Timothy O'Leary
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-09-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/62912