Transcriptional Regulation of <i>RUNX1</i>: An Informatics Analysis

Transcriptional Regulation of <i>RUNX1</i>: An Informatics Analysis

The <i>RUNX1/AML1</i> gene encodes a developmental transcription factor that is an important regulator of haematopoiesis in vertebrates. Genetic disruptions to the <i>RUNX1</i> gene are frequently associated with acute myeloid leukaemia. Gene regulatory elements (REs), such a...

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Bibliographic Details
Main Authors: Amarni L. Thomas, Judith Marsman, Jisha Antony, William Schierding, Justin M. O’Sullivan, Julia A. Horsfield
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Genes
Subjects:
acute myeloid leukaemia
<i>RUNX1</i>
transcription
enhancer
silencer
chromatin
Online Access:https://www.mdpi.com/2073-4425/12/8/1175

Internet

https://www.mdpi.com/2073-4425/12/8/1175

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