A Comparative Analysis of 5-Azacytidine- and Zebularine-Induced DNA Demethylation
The nonmethylable cytosine analogs, 5-azacytidine and zebularine, are widely used to inhibit DNA methyltransferase activity and reduce genomic DNA methylation. In this study, whole-genome bisulfite sequencing is used to construct maps of DNA methylation with single base pair resolution in Arabidopsi...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Oxford University Press
2016-09-01
|
Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.116.030262 |