Anticancer Activity and Cisplatin Binding Ability of Bis-Quinoline and Bis-Isoquinoline Derived [Pd2L4]4+ Metallosupramolecular Cages

Anticancer Activity and Cisplatin Binding Ability of Bis-Quinoline and Bis-Isoquinoline Derived [Pd2L4]4+ Metallosupramolecular Cages

New bis-quinoline (Lq) and bis-isoquinoline-based (Liq) ligands have been synthesized, along with their respective homoleptic [Pd2(Lq or Liq)4]4+ cages (Cq and Ciq). The ligands and cages were characterized by 1H, 13C and diffusion ordered (DOSY) NMR spectroscopies, high resolution electrospray ioni...

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Bibliographic Details
Main Authors: Roan A. S. Vasdev, Lachlan F. Gaudin, Dan Preston, Jackmil P. Jogy, Gregory I. Giles, James D. Crowley
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Chemistry
Subjects:
palladium(II)
anticancer
self-assembly
metallosupramolecular
quinoline
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2018.00563/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2018.00563/full

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