Fisetin Attenuates Paracetamol-Induced Hepatotoxicity by Regulating CYP2E1 Enzyme

Fisetin Attenuates Paracetamol-Induced Hepatotoxicity by Regulating CYP2E1 Enzyme

Abstract Paracetamol is one of the drugs that cause hepatic damage. Fisetin has wide pharmacological effects such as anticancer, antiinflammatory and antioxidant. We aimed to evaluate the possible protective effect of fisetin on paracetamol-induced hepatotoxicity. Fisetin was administered at 25 and...

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Bibliographic Details
Main Authors: RUSTEM A. UGAN, ELIF CADIRCI, HARUN UN, IRFAN CINAR, MUHAMMET A. GURBUZ
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2023-04-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Fisetin
rat
paracetamol
hepatotoxicity
TNF-α
CYP2E1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652023000300702&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652023000300702&lng=en&tlng=en

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