17-β estradiol exerts anti-inflammatory effects through activation of Nrf2 in mouse embryonic fibroblasts.

Several reports indicate crosstalk between the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) and estrogen, which has a protective effect in colorectal cancer (CRC). The aim of this study was to investigate the role of Nrf2 signaling in the anti-inflammatory effect of estrog...

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Bibliographic Details
Main Authors: Chin-Hee Song, Nayoung Kim, Do-Hee Kim, Ha-Na Lee, Young-Joon Surh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0221650