Plasminogen activator inhibitor 1 and gestational diabetes: the causal relationship

Abstract Plasminogen activator inhibitor 1 (PAI-1) also known as serpin E1 or endothelial plasminogen activator inhibitor, is produced from endothelial cells and adipose tissue. PAI-1 inhibits tissue plasminogen activator (tPA) and urokinase (uPA) preventing activation of plasminogen and fibrinolysi...

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Main Authors: Gaber El-Saber Batiha, Hayder M. Al-kuraishy, Thabat J. Al-Maiahy, Ali K. Al-Buhadily, Hebatallah M. Saad, Ali I. Al-Gareeb, Jesus Simal-Gandara
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-022-00900-2