Loss of <i>Runx1</i> Induces Granulosa Cell Defects and Development of Ovarian Tumors in the Mouse
Genetic alterations of the <i>RUNX1</i> gene are associated with a variety of malignancies, including female-related cancers. The role of <i>RUNX1</i> as either a tumor suppressor gene or an oncogene is tissue-dependent and varies based on the cancer type. Both the amplificat...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/22/14442 |