Loss of <i>Runx1</i> Induces Granulosa Cell Defects and Development of Ovarian Tumors in the Mouse

Genetic alterations of the <i>RUNX1</i> gene are associated with a variety of malignancies, including female-related cancers. The role of <i>RUNX1</i> as either a tumor suppressor gene or an oncogene is tissue-dependent and varies based on the cancer type. Both the amplificat...

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Bibliographic Details
Main Authors: Kamiya Bridges, Humphrey H.-C. Yao, Barbara Nicol
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/22/14442