Alterations in Intrinsic and Synaptic Properties of Hippocampal CA1 VIP Interneurons During Aging

Alterations in Intrinsic and Synaptic Properties of Hippocampal CA1 VIP Interneurons During Aging

Learning and memory deficits are hallmarks of the aging brain, with cortical neuronal circuits representing the main target in cognitive deterioration. While GABAergic inhibitory and disinhibitory circuits are critical in supporting cognitive processes, their roles in age-related cognitive decline r...

Full description

Bibliographic Details
Main Authors: Ruggiero Francavilla, Alexandre Guet-McCreight, Sona Amalyan, Chin Wai Hui, Dimitry Topolnik, Félix Michaud, Beatrice Marino, Marie-Ève Tremblay, Frances K. Skinner, Lisa Topolnik
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
circuit disinhibition
VIP
action potential
synapse
hippocampus
aging
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.554405/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.554405/full

Similar Items