Reduction in Kv Current Enhances the Temporal Dispersion of the Action Potential in Diabetic Myocytes: Insights From a Novel Repolarization Algorithm

Reduction in Kv Current Enhances the Temporal Dispersion of the Action Potential in Diabetic Myocytes: Insights From a Novel Repolarization Algorithm

BackgroundDiabetes is associated with prolongation of the QT interval of the electrocardiogram and enhanced dispersion of ventricular repolarization, factors that, together with atherosclerosis and myocardial ischemia, may promote the occurrence of electrical disorders. Thus, we tested the possibili...

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Bibliographic Details
Main Authors: Marianna Meo, Olivier Meste, Sergio Signore, Andrea Sorrentino, Antonio Cannata, Yu Zhou, Alex Matsuda, Marco Luciani, Ramaswamy Kannappan, Polina Goichberg, Annarosa Leri, Piero Anversa, Marcello Rota
Format: Article
Language:English
Published: Wiley 2016-02-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
diabetes
electrophysiology
repolarization
variability
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.115.003078

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.115.003078

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