The impact of microglial activation on blood-brain barrier in brain diseases

The impact of microglial activation on blood-brain barrier in brain diseases

The blood-brain barrier (BBB), constituted by an extensive network of endothelial cells together with neurons and glial cells, including microglia, forms the neurovascular unit. The crosstalk between these cells guarantees a proper environment for brain function. In this context, changes in the endo...

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Bibliographic Details
Main Authors: Anna Carolina Carvalho Da Fonseca, Diana Isabel Lourenço Matias, Celina eGarcia, Rackele eAmaral, Luiz Henrique Geraldo, Catarina eFreitas, Flavia Regina Souza Lima
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Blood-Brain Barrier
Brain Diseases
Endothelium
Microglia
Neuroinflammation
microglial activation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00362/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00362/full

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