Rapid disease progression on immune checkpoint inhibitors in young patients with stage IV melanoma

Rapid disease progression on immune checkpoint inhibitors in young patients with stage IV melanoma

BackgroundImmune checkpoint inhibitors (ICIs) are the standard of care for metastatic cutaneous melanoma (mCM) patients, but their efficacy in young adults aged less than 40 years remains unclear.Materials and methodsWe retrospectively analyzed 303 stage IV melanoma patients of different ages treate...

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Bibliographic Details
Main Authors: Devayani Machiraju, Sarah Schäfer, Philip Beckhove, Jasmin Roth, Carsten Schulz, Jessica C. Hassel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Medicine
Subjects:
melanoma
young adults
memory T cells
soluble immune checkpoint proteins
age
immune checkpoint inhibitors (ICI)
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1117816/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2023.1117816/full

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