A dual‐functional BODIPY‐based molecular rotor probe reveals different viscosity of protein aggregates in live cells

A dual‐functional BODIPY‐based molecular rotor probe reveals different viscosity of protein aggregates in live cells

Abstract Aberrant protein aggregation leads to various human diseases, but little is known about the physical chemical properties of these aggregated proteins in cells. Herein, we developed a boron‐dipyrromethene (BODIPY)‐based HaloTag probe, whose conjugation to HaloTag‐fused proteins allows us to...

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Bibliographic Details
Main Authors: Baoxing Shen, Kwan Ho Jung, Songtao Ye, Conner A. Hoelzel, Charles H. Wolstenholme, He Huang, Yu Liu, Xin Zhang
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Aggregate
Subjects:
fluorescence microscopy
fluorescent probes
protein aggregates
Online Access:https://doi.org/10.1002/agt2.301

Internet

https://doi.org/10.1002/agt2.301

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