Inositol Requiring Enzyme (IRE), a multiplayer in sensing endoplasmic reticulum stress

The endoplasmic reticulum (ER) can sense a wide variety of external and internal perturbations and responds by mounting stress coping responses, such as the unfolded protein response (UPR). The UPR is composed of three stress sensors, namely IRE1α, PERK, and ATF6 that are activated to re-establish E...

Full description

Bibliographic Details
Main Authors: Zhixin Zhou, Qian Wang, Marek Michalak
Format: Article
Language:English
Published: Taylor & Francis Group 2021-11-01
Series:Animal Cells and Systems
Subjects:
Online Access:http://dx.doi.org/10.1080/19768354.2021.2020901