Hypoxia-induced mitochondrial DNA release promotes proliferation of pulmonary arterial smooth muscle cells via activating cGAS-STING pathway
Objective To investigate the role and possible mechanism of mitochondrial DNA (mtDNA) release in the proliferation of rat pulmonary arterial smooth muscle cells (RPASMCs) induced by hypoxia. Methods ① RPASMCs were divided into normoxia group, hypoxia 24-hour group and hypoxia 48-hour group (n=3 for...
Main Authors: | , , , |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Third Military Medical University
2022-01-01
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Series: | Di-san junyi daxue xuebao |
Subjects: | |
Online Access: | http://aammt.tmmu.edu.cn/Upload/rhtml/202107134.htm |