Prolactin Variants in Human Pituitaries and Pituitary Adenomas Identified With Two-Dimensional Gel Electrophoresis and Mass Spectrometry

Prolactin Variants in Human Pituitaries and Pituitary Adenomas Identified With Two-Dimensional Gel Electrophoresis and Mass Spectrometry

Human prolactin (hPRL) plays multiple roles in growth, metabolism, development, reproduction, and immunoregulation, which is an important protein synthesized in a pituitary. Two-dimensional gel electrophoresis (2DE) is an effective method in identity of protein variants for in-depth insight into fun...

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Bibliographic Details
Main Authors: Shehua Qian, Yongmei Yang, Na Li, Tingting Cheng, Xiaowei Wang, Jianping Liu, Xuejun Li, Dominic M. Desiderio, Xianquan Zhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Endocrinology
Subjects:
prolactin variants
human pituitary
post-translational modifications
mass spectrometry
variant pattern
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00468/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00468/full

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