Pre-cART Immune Parameters in People Living With HIV Might Help Predict CD8+ T-Cell Characteristics, Inflammation Levels, and Reservoir Composition After Effective cART

Pre-cART Immune Parameters in People Living With HIV Might Help Predict CD8+ T-Cell Characteristics, Inflammation Levels, and Reservoir Composition After Effective cART

Background: Combined antiretroviral treatment (cART) for HIV infection is highly effective in controlling viral replication. However, it cannot achieve a sterilizing cure.  Several strategies have been proposed to achieve a functional cure, some of them based on immune-mediated clearing of persiste...

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Bibliographic Details
Main Authors: Jimena Salido, Alejandro Czernikier, Cesar Trifone, María Laura Polo, María Ines Figueroa, Alejandra Urioste, Pedro Cahn, Omar Sued, Horacio Salomon, Natalia Laufer, Yanina Ghiglione, Gabriela Turk
Format: Article
Language:English
Published: Case Western Reserve University 2021-10-01
Series:Pathogens and Immunity
Subjects:
HIV; persistence; CD8 T cells; CD4 T cells; inflammation; viral reservoir
Online Access:https://www.paijournal.com/index.php/paijournal/article/view/447

Internet

https://www.paijournal.com/index.php/paijournal/article/view/447

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