Multidrug-loaded liposomes prevent ischemic stroke through intranasal administration

Multidrug-loaded liposomes prevent ischemic stroke through intranasal administration

Baicalin (BA), a multi-target neuroprotective agent, has poor solubility resulting in low bioavailability. In this study, multidrug-loaded liposomes were prepared by encapsulating BA, borneol (BO) and cholic acid (CA) to prevent ischemic stroke. BBC-LP were administered intranasally (i.n.) to delive...

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Bibliographic Details
Main Authors: Shuang Yu, Dan Li, Ai Shi, Yu Long, Jie Deng, Yin Ma, Xiaoqiu Li, Jing Wen, Yue Hu, Xiaofang He, Yuanyuan Wu, Nan Li, Mengnan Zhao
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Baicalin
Liposome
Ischemic stroke
Intranasal administration
Network pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222300330X

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http://www.sciencedirect.com/science/article/pii/S075333222300330X

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