E-cigarette and food flavoring diacetyl alters airway cell morphology, inflammatory and antiviral response, and susceptibility to SARS-CoV-2

Summary Diacetyl (DA) is an α-diketone that is used to flavor microwave popcorn, coffee, and e-cigarettes. Occupational exposure to high levels of DA causes impaired lung function and obstructive airway disease. Additionally, lower levels of DA exposure dampen host defenses in vitro. Understanding D...

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Bibliographic Details
Main Authors: Stephanie N. Langel, Francine L. Kelly, David M. Brass, Andrew E. Nagler, Dylan Carmack, Joshua J. Tu, Tatianna Travieso, Ria Goswami, Sallie R. Permar, Maria Blasi, Scott M. Palmer
Format: Article
Language:English
Published: Nature Publishing Group 2022-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-00855-3