Feasibility of Enhancing Skin Permeability of Acyclovir through Sterile Topical Lyophilized Wafer on Self-Dissolving Microneedle-Treated Skin

Acyclovir is an antiviral drug that is frequently prescribed for the herpes virus. However, the drug requires frequent dosing due to limited bioavailability (10–26.7%). The rationale of the present study was to develop a self-dissolving microneedle system for local and systemic delivery of acyclovir...

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Bibliographic Details
Main Authors: Uzair Nagra, Kashif Barkat, Muhammad U Ashraf, Maryam Shabbir
Format: Article
Language:English
Published: SAGE Publishing 2022-04-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/15593258221097594