Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments

Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments

Abstract Background Perinatal HIV infection negatively impacts cognitive functioning of children, main domains affected are working memory, processing speed and executive function. Early ART, even when interrupted, improves neurodevelopmental outcomes. Diffusion tension imaging (DTI) is a sensitive...

Full description

Bibliographic Details
Main Authors: Christelle Ackermann, Savvas Andronikou, Muhammad G. Saleh, Martin Kidd, Mark F. Cotton, Ernesta M. Meintjes, Barbara Laughton
Format: Article
Language:English
Published: BMC 2020-05-01
Series:AIDS Research and Therapy
Subjects:
HIV
Cognitive functioning
ARV
DTI
Functional anisotropy
White matter
Online Access:http://link.springer.com/article/10.1186/s12981-020-00278-z

Internet

http://link.springer.com/article/10.1186/s12981-020-00278-z

Similar Items