TRIM21–SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis

TRIM21–SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis

Abstract Background The main strategy against nasopharyngeal carcinoma (NPC) is radiotherapy. However, radioresistance mediated recurrence is a leading clinical bottleneck in NPC. Revealing the mechanism of NPC radioresistance will help improve the therapeutic effect. Methods In this study, the role...

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Bibliographic Details
Main Authors: Panpan Zhang, Xiaomin Li, Qiuping He, Lulu Zhang, Keqing Song, Xiaojing Yang, Qingmei He, Yaqin Wang, Xiaohong Hong, Jun Ma, Na Liu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
Apoptosis
GMPS
Nasopharyngeal carcinoma
SERPINB5
TRIM21
TP53
Online Access:https://doi.org/10.1186/s12929-020-0625-7

Internet

https://doi.org/10.1186/s12929-020-0625-7

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