Bisoprolol therapy does not reduce right ventricular sympathetic activity in pulmonary arterial hypertension patients

Right ventricular (RV) function and autonomic dysfunction are important determinants of morbidity and mortality in patients with pulmonary arterial hypertension (PAH). Although successful in animal studies, effects of beta-blocker therapy on RV function in clinical trials were disappointing. To unde...

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Bibliographic Details
Main Authors: Mischa T. Rijnierse, Joanne A. Groeneveldt, Jasmijn S.J.A. van Campen, Karin de Boer, Cathelijne E.E. van der Bruggen, Hendrik J. Harms, Pieter G. Raijmakers, Adriaan A. Lammertsma, Paul Knaapen, Harm Jan Bogaard, Berend E. Westerhof, Anton Vonk Noordegraaf, Cornelis P. Allaart, Frances S. de Man
Format: Article
Language:English
Published: Wiley 2020-04-01
Series:Pulmonary Circulation
Online Access:https://doi.org/10.1177/2045894019873548