Recovery of strain-resolved genomes from human microbiome through an integration framework of single-cell genomics and metagenomics
Abstract Background Obtaining high-quality (HQ) reference genomes from microbial communities is crucial for understanding the phylogeny and function of uncultured microbes in complex microbial ecosystems. Despite improvements in bioinformatic approaches to generate curated metagenome-assembled genom...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-10-01
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Series: | Microbiome |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40168-021-01152-4 |