Analyzing bovine OCT4 and NANOG enhancer activity in pluripotent stem cells using fluorescent protein reporters.

Green fluorescent protein (GFP) reporters controlled by the regulatory region of OCT4 and NANOG-two master regulators for pluripotency are widely used in studies of pluripotent stem cell establishment and embryo development. Alongside the challenge in establishing bovine pluripotent stem cells, the...

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Bibliographic Details
Main Authors: Delun Huang, Ling Wang, Neil C Talbot, Chang Huang, Liping Pu, Xiuling Zhao, Xiuchun Tian, Ming Zhang, Young Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6173392?pdf=render