Circulating protein biomarkers of pharmacodynamic activity of sunitinib in patients with metastatic renal cell carcinoma: modulation of VEGF and VEGF-related proteins
<p>Abstract</p> <p>Background</p> <p>Sunitinib malate (SUTENT<sup>®</sup>) is an oral, multitargeted tyrosine kinase inhibitor, approved multinationally for the treatment of advanced RCC and of imatinib-resistant or – intolerant GIST. The purpose of this stu...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2007-07-01
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Series: | Journal of Translational Medicine |
Online Access: | http://www.translational-medicine.com/content/5/1/32 |