Effect of acetazolamide on pulmonary vascular haemodynamics in patients with COPD going to altitude: a randomised, placebo-controlled, double-blind trial

Background COPD may predispose to symptomatic pulmonary hypertension at high altitude. We investigated haemodynamic changes in lowlanders with COPD ascending to 3100 m and evaluated whether preventive acetazolamide treatment would attenuate the altitude-induced increase in pulmonary artery pressure...

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Main Authors: Mona Lichtblau, Stéphanie Saxer, Laura Mayer, Ulan Sheraliev, Maamed Mademilov, Michael Furian, Aline Buergin, Philipp M. Schweiwiller, Simon R. Schneider, Felix C. Tanner, Talant Sooronbaev, Konrad E. Bloch, Silvia Ulrich
Format: Article
Language:English
Published: European Respiratory Society 2023-04-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/9/2/00412-2022.full