HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property

HPMC/PVP K90 Dissolving Microneedles Fabricated from 3D-Printed Master Molds: Impact on Microneedle Morphology, Mechanical Strength, and Topical Dissolving Property

Three-dimensional (3D) printing can be used to fabricate custom microneedle (MN) patches instead of the conventional method. In this work, 3D-printed MN patches were utilized to fabricate a MN mold, and the mold was used to prepare dissolving MNs for topical lidocaine HCl (L) delivery through the sk...

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Bibliographic Details
Main Authors: Baramee Chanabodeechalermrung, Tanpong Chaiwarit, Siripat Chaichit, Suruk Udomsom, Phornsawat Baipaywad, Patnarin Worajittiphon, Pensak Jantrawut
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Polymers
Subjects:
dissolving microneedles
3D printing
lidocaine HCl
intradermal drug delivery
hydroxypropyl methylcellulose
PVP K90
Online Access:https://www.mdpi.com/2073-4360/16/4/452

Internet

https://www.mdpi.com/2073-4360/16/4/452

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