Embryonic caffeine exposure acts via A1 adenosine receptors to alter adult cardiac function and DNA methylation in mice.

Embryonic caffeine exposure acts via A1 adenosine receptors to alter adult cardiac function and DNA methylation in mice.

Evidence indicates that disruption of normal prenatal development influences an individual's risk of developing obesity and cardiovascular disease as an adult. Thus, understanding how in utero exposure to chemical agents leads to increased susceptibility to adult diseases is a critical health r...

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Bibliographic Details
Main Authors: Daniela L Buscariollo, Xiefan Fang, Victoria Greenwood, Huiling Xue, Scott A Rivkees, Christopher C Wendler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3903656?pdf=render

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http://europepmc.org/articles/PMC3903656?pdf=render

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