CIB1 depletion with docetaxel or TRAIL enhances triple-negative breast cancer cell death

CIB1 depletion with docetaxel or TRAIL enhances triple-negative breast cancer cell death

Abstract Background Patients diagnosed with triple negative breast cancer (TNBC) have limited treatment options and often suffer from resistance and toxicity due to chemotherapy. We previously found that depleting calcium and integrin-binding protein 1 (CIB1) induces cell death selectively in TNBC c...

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Bibliographic Details
Main Authors: Alexander H. Chung, Tina M. Leisner, Gabrielle J. Dardis, Marissa M. Bivins, Alana L. Keller, Leslie V. Parise
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Cancer Cell International
Subjects:
CIB1
TRAIL
Apoptosis
Triple-negative breast cancer
Chemoresistance
Online Access:http://link.springer.com/article/10.1186/s12935-019-0740-2

Internet

http://link.springer.com/article/10.1186/s12935-019-0740-2

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