Exploring the dynamics and influencing factors of CD4 T cell activation using single-cell RNA-seq

Exploring the dynamics and influencing factors of CD4 T cell activation using single-cell RNA-seq

Summary: T cell activation is a key event in adaptive immunity. However, the dynamics and influencing factors of T cell activation remain unclear. Here, we analyzed CD4 T cells that were stimulated with anti-CD3/CD28 under several conditions to explore the factors affecting T cell activation. We fou...

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Bibliographic Details
Main Authors: Hui Li, Hongyi Liu, Yifei Liu, Xuefei Wang, Shiya Yu, Hongwen Huang, Xiangru Shen, Qi Zhang, Ni Hong, Wenfei Jin
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Immune response
Components of the immune system
Specialized functions of cells
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223016656

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http://www.sciencedirect.com/science/article/pii/S2589004223016656

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