In silico Drug Repurposing of Anticancer Drug 5-FU and Analogues Against SARS-CoV-2 Main Protease: Molecular Docking, Molecular Dynamics Simulation, Pharmacokinetics and Chemical Reactivity Studies

In silico Drug Repurposing of Anticancer Drug 5-FU and Analogues Against SARS-CoV-2 Main Protease: Molecular Docking, Molecular Dynamics Simulation, Pharmacokinetics and Chemical Reactivity Studies

Aristote Matondo,1 Washington Dendera,2 Bienfait Kabuyaya Isamura,1– 3 Koto-te-Nyiwa Ngbolua,4 Hilaire VS Mambo,1 Mayaliwa Muzomwe,1 Virima Mudogo1 1Department of Chemistry, University of Kinshasa, Kinshasa, Democratic Republic of the Congo; 2Department of Chemistry, Rhodes University, Makhanda, Eas...

Full description

Bibliographic Details
Main Authors: Matondo A, Dendera W, Isamura BK, Ngbolua KTN, Mambo HVS, Muzomwe M, Mudogo V
Format: Article
Language:English
Published: Dove Medical Press 2022-08-01
Series:Advances and Applications in Bioinformatics and Chemistry
Subjects:
drug repurposing
5-fluorouracil
sars-cov-2
molecular docking
molecular dynamics simulation
admet
Online Access:https://www.dovepress.com/in-silico-drug-repurposing-of-anticancer-drug-5-fu-and-analogues-again-peer-reviewed-fulltext-article-AABC

Internet

https://www.dovepress.com/in-silico-drug-repurposing-of-anticancer-drug-5-fu-and-analogues-again-peer-reviewed-fulltext-article-AABC

Similar Items