Aglianico Grape Seed Semi-Polar Extract Exerts Anticancer Effects by Modulating MDM2 Expression and Metabolic Pathways

Aglianico Grape Seed Semi-Polar Extract Exerts Anticancer Effects by Modulating MDM2 Expression and Metabolic Pathways

Grapevine (<i>Vitis vinifera</i> L.) seeds are rich in polyphenols including proanthocyanidins, molecules with a variety of biological effects including anticancer action. We have previously reported that the grape seed semi-polar extract of Aglianico cultivar (AGS) was able to induce ap...

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Bibliographic Details
Main Authors: Rossana Cuciniello, Francesco Di Meo, Maria Sulli, Olivia Costantina Demurtas, Mirella Tanori, Mariateresa Mancuso, Clizia Villano, Riccardo Aversano, Domenico Carputo, Alfonso Baldi, Gianfranco Diretto, Stefania Filosa, Stefania Crispi
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
grape-seed extract
apoptosis
MDM2
gene expression
cancer metabolism
proanthocyanidins
Online Access:https://www.mdpi.com/2073-4409/12/2/210

Internet

https://www.mdpi.com/2073-4409/12/2/210

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