Oscillatory dynamics of Rac1 activity in Dictyostelium discoideum amoebae.

Small GTPases of the Rho family play a central role in the regulation of cell motility by controlling the remodeling of the actin cytoskeleton. In the amoeboid cells of Dictyostelium discoideum, the active form of the Rho GTPase Rac1 regulates actin polymerases at the leading edge and actin filament...

Full description

Bibliographic Details
Main Authors: Marko Šoštar, Maja Marinović, Vedrana Filić, Nenad Pavin, Igor Weber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-12-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1012025