Protein innovation through template switching in the Saccharomyces cerevisiae lineage

Abstract DNA polymerase template switching between short, non-identical inverted repeats (IRs) is a genetic mechanism that leads to the homogenization of IR arms and to IR spacer inversion, which cause multinucleotide mutations (MNMs). It is unknown if and how template switching affects gene evoluti...

Full description

Bibliographic Details
Main Authors: May Abraham, Einat Hazkani-Covo
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-01736-y