α-Synuclein is required for sperm exocytosis at a post-fusion stage

The sperm acrosome is a large dense-core granule whose contents are secreted by regulated exocytosis at fertilization through the opening of numerous fusion pores between the acrosomal and plasma membranes. In other cells, the nascent pore generated when the membrane surrounding a secretory vesicle...

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Bibliographic Details
Main Authors: Micaela Vanina Buzzatto, María Victoria Berberián, Ary Lautaro Di Bartolo, Diego Masone, Claudia Nora Tomes
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1125988/full