LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma

LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma

Summary: Hepatocellular carcinoma (HCC) is highly heterogeneous, and stemness signatures are frequently elevated in HCC tumor cells to generate heterogeneous subtypes via multidirectional differentiation. However, the mechanisms affecting the regulation of stemness in HCC remain unclear. In this stu...

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Bibliographic Details
Main Authors: Jianping Liao, Jiahong Wang, Yu Xu, Yong Wu, Meifeng Wang, Qiudong Zhao, Xiaodan Tan, Yan Meng, Lixin Wei, Aimin Huang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:iScience
Subjects:
Cell biology
Stem cells research
Cancer systems biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223008313

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http://www.sciencedirect.com/science/article/pii/S2589004223008313

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