A systems radiation biology approach to unravel the role of chronic low-dose-rate gamma-irradiation in inducing premature senescence in endothelial cells.

<h4>Purpose</h4>The aim of this study was to explore the effects of chronic low-dose-rate gamma-radiation at a multi-scale level. The specific objective was to obtain an overall view of the endothelial cell response, by integrating previously published data on different cellular endpoint...

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Bibliographic Details
Main Authors: Gabriele Babini, Giorgio Baiocco, Sofia Barbieri, Jacopo Morini, Traimate Sangsuwan, Siamak Haghdoost, Ramesh Yentrapalli, Omid Azimzadeh, Charlotte Rombouts, An Aerts, Roel Quintens, Teni Ebrahimian, Mohammed Abderrafi Benotmane, Raghda Ramadan, Sarah Baatout, Soile Tapio, Mats Harms-Ringdahl, Andrea Ottolenghi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0265281