Effect of alendronate sodium plus vitamin D3 tablets on knee joint structure and osteoarthritis pain: a multi-center, randomized, double-blind, placebo-controlled study protocol

Effect of alendronate sodium plus vitamin D3 tablets on knee joint structure and osteoarthritis pain: a multi-center, randomized, double-blind, placebo-controlled study protocol

Abstract Background Osteoarthritis (OA) is a major cause of pain and disability worldwide. Despite the relatively high burden of the disease, the currently available non-surgical treatment options are directed towards symptomatic relief. Therefore, we propose the use of alendronate as a disease modi...

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Bibliographic Details
Main Authors: Hui-ming Peng, Xi-sheng Weng, Ye Li, Bin Feng, Wenwei Qian, Dao-zhang Cai, Chang Zhao, Zhen-jun Yao, Yi Yang, Chi Zhang, Shengcheng Wan
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Musculoskeletal Disorders
Subjects:
osteoarthritis
pain
alendronate
vitamin D3
trial
Online Access:https://doi.org/10.1186/s12891-022-05521-4

Internet

https://doi.org/10.1186/s12891-022-05521-4

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