The Effect of Elevated Alanine Transaminase on Non-invasive Prenatal Screening Failures

The Effect of Elevated Alanine Transaminase on Non-invasive Prenatal Screening Failures

ObjectiveTo determine the effects of alanine transaminase (ALT) levels on the screening failure rates or “no calls” due to low fetal fraction (FF) to obtain a result in non-invasive prenatal screening (NIPS).MethodsNIPS by sequencing and liver enzyme measurements were performed in 7,910 pregnancies...

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Bibliographic Details
Main Authors: Ping Chen, Longwei Qiao, Sheng Zhang, Jieyu Jin, Jun Cao, Yuqiong Zhang, Haoyu Tang, Zheng Yu, Jingye Shi, JingPing Yin, Yuting Liang, Xiao Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Medicine
Subjects:
non-invasive prenatal screening
fetal fraction
cell-free DNA
ALT
multivariable linear regression models
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.875588/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2022.875588/full

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