Role of A2B adenosine receptor-dependent adenosine signaling in multi-walled carbon nanotube-triggered lung fibrosis in mice

Role of A2B adenosine receptor-dependent adenosine signaling in multi-walled carbon nanotube-triggered lung fibrosis in mice

Abstract Background Multi-walled carbon nanotube (MWCNT)-induced lung fibrosis leads to health concerns in human. However, the mechanisms underlying fibrosis pathogenesis remains unclear. The adenosine (ADO) is produced in response to injury and serves a detrimental role in lung fibrosis. In this st...

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Bibliographic Details
Main Authors: Biying Liu, Qizheng Bing, Siyu Li, Bing Han, Jingjing Lu, Ruiqi Baiyun, Xiaoya Zhang, Yueying Lv, Hao Wu, Zhigang Zhang
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Journal of Nanobiotechnology
Subjects:
Multi-walled carbon nanotubes
Lung fibrosis
Adenosine
A2B adenosine receptor
Transforming growth factor-β1
Follistatin-like 1
Online Access:http://link.springer.com/article/10.1186/s12951-019-0478-y

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http://link.springer.com/article/10.1186/s12951-019-0478-y

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