PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanism

PD-1/PD-L1 Inhibitor-Associated Myocarditis: Epidemiology, Characteristics, Diagnosis, Treatment, and Potential Mechanism

Immune checkpoint inhibitors (ICIs) induce T-cell activation against cancer cells, and due to their anti-tumor function in multiple cancers, ICIs have been considered an important option for oncotherapy. PD-1/PD-L1 inhibitors are now widely used as ICIs for many types of cancers in clinical practice...

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Bibliographic Details
Main Authors: Hao Dong, Yihang Qi, Xiangyi Kong, Zhongzhao Wang, Yi Fang, Jing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
immunotherapy
myocarditis
epidemiology
mechanism
PD-1/PD-L1 inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.835510/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.835510/full

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