Improved Detection of Microsatellite Instability in Early Colorectal Lesions.

Improved Detection of Microsatellite Instability in Early Colorectal Lesions.

Microsatellite instability (MSI) occurs in over 90% of Lynch syndrome cancers and is considered a hallmark of the disease. MSI is an early event in colon tumor development, but screening polyps for MSI remains controversial because of reduced sensitivity compared to more advanced neoplasms. To incre...

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Bibliographic Details
Main Authors: Jeffery W Bacher, Chelsie K Sievers, Dawn M Albrecht, Ian C Grimes, Jennifer M Weiss, Kristina A Matkowskyj, Rashmi M Agni, Irina Vyazunova, Linda Clipson, Douglas R Storts, Andrew T Thliveris, Richard B Halberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0132727

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https://doi.org/10.1371/journal.pone.0132727

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