An Aurora kinase inhibitor, AMG900, inhibits glioblastoma cell proliferation by disrupting mitotic progression

Abstract The Aurora kinase family of serine/threonine protein kinases comprises Aurora A, B, and C and plays an important role in mitotic progression. Several inhibitors of Aurora kinase have been developed as anti‐cancer therapeutics. Here, we examined the effects of a pan‐Aurora kinase inhibitor,...

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Bibliographic Details
Main Authors: Jaewook Ryu, Jaehyuk Pyo, Chang‐Woo Lee, Ja‐Eun Kim
Format: Article
Language:English
Published: Wiley 2018-11-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.1771