An Aurora kinase inhibitor, AMG900, inhibits glioblastoma cell proliferation by disrupting mitotic progression
Abstract The Aurora kinase family of serine/threonine protein kinases comprises Aurora A, B, and C and plays an important role in mitotic progression. Several inhibitors of Aurora kinase have been developed as anti‐cancer therapeutics. Here, we examined the effects of a pan‐Aurora kinase inhibitor,...
Main Authors: | Jaewook Ryu, Jaehyuk Pyo, Chang‐Woo Lee, Ja‐Eun Kim |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2018-11-01
|
Series: | Cancer Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/cam4.1771 |
Similar Items
-
The functional diversity of Aurora kinases: a comprehensive review
by: Estelle Willems, et al.
Published: (2018-09-01) -
Aurora A's functions during mitotic exit: the Guess Who game
by: David eReboutier, et al.
Published: (2015-12-01) -
Unweaving the mitotic spindle: A focus on Aurora kinase inhibitors in lung cancer
by: Alessio Stefani, et al.
Published: (2022-10-01) -
Aurora kinases orchestrate mitosis; who are the players?
by: Molla Annie
Published: (2010-08-01) -
Aurora at the pole and equator: overlapping functions of Aurora kinases in the mitotic spindle
by: Helfrid Hochegger, et al.
Published: (2013-01-01)