An enterovirus A71 virus-like particle with replaced loops confers partial cross-protection in mice

An enterovirus A71 virus-like particle with replaced loops confers partial cross-protection in mice

Enterovirus A71 (EV-A71), coxsackievirus A16 (CV-A16), and CV-A10 belong to the main prevailing types causing hand-foot-and-mouth disease. Since EV-A71 monovalent vaccine does not confer cross-protection, developing a multivalent vaccine is essential. In this study, a trivalent chimeric virus-like p...

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Bibliographic Details
Main Authors: Xin Liu, Hanyu Zhu, Mei Wang, Ning Zhang, Jing Wang, Wenbian Tan, Guochuan Wu, Pei Yu, Hongbo Liu, Qiliang Liu
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Virus Research
Subjects:
Hand-foot-and-mouth disease
Enterovirus
Virus-like particle
Chimeric vaccine
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170223001971

Internet

http://www.sciencedirect.com/science/article/pii/S0168170223001971

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