Cytochrome P450 2C24: expression, tissue distribution, high-throughput assay, and pharmacological inhibition
Cytochrome P450 (CYP)-mediated epoxidation of arachidonic acid (AA) contributes to important biological functions, including the pain-relieving responses produced by analgesic drugs. However, the relevant epoxygenase(s) remain unidentified. Presently, we describe the tissue distribution, high-throug...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2012-04-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383512000196 |